Herbal supplements and heart medicines may not mix, Your blood pressure, if you also take a drug to treat high blood pressure, Beta blockers, such as atenolol (Tenormin), nadolol (Corgard) or propranolol (Inderal LA, Innopran XL), Calcium channel blockers, such as diltiazem, nifedipine (Procardia) and verapamil (Calan SR, Verelan), Nitrates, such as nitroglycerin (Nitrostat, Nitro-Dur, others) and isosorbide (Isordil, Bidil), Statins, such as atorvastatin (Lipitor), lovastatin (Altoprev) and rosuvastatin (Crestor), Anti-rejection medicine, also called immunosuppressant medicine, such as cyclosporine (Gengraf, Neoral, Sandimmune). Accessed Sept. 7, 2022.
Consult a doctor or other health care professional for diagnosis and treatment of medical conditions. Alternative drugs to the conditions Isosorbide mononitrate treats: Angina High blood pressure Stable angina Chest pain Heart disease Heart attack Angina unstable Heart disease congenital Coronary heart disease Heart failure Pulse Heart rate irregular Coronary artery spasm Angioplasty If you miss a dose, take it as soon as you remember. That's why you need to talk with your health care provider before you take herbal supplements if you take prescription medicines. See also: nitroglycerin side effects in more detail. Isosorbide may not work as well after you have taken it for some time or if you have taken many doses. View World Anti-Doping Agency classifications, Prevention of Thromboembolism in Atrial Fibrillation, Prosthetic Heart Valves - Thrombosis Prophylaxis, Prosthetic Heart Valves - Mechanical Valves - Thrombosis Prophylaxis, Revascularization Procedures - Prophylaxis. Other medications may be prescribed by your doctor for these conditions. Vascular dilatation can precipitate venous pooling with decreased return to the heart, hypotension and reflex tachycardia. Check out these best-sellers and special offers on books and newsletters from Mayo Clinic Press. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch. 1996 Dec;3(12):802-806. doi: 10.1097/00045391-199612000-00003. Always let your doctor and pharmacist know about any other medications or supplements (including prescribed and over-the-counter medications, vitamins, and dietary or herbal supplements) that you are currently taking. With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. include protected health information. If you notice any other effects, check with your healthcare professional. We study 23,548 Isosorbide mononitrate users.
Isosorbide - StatPearls - NCBI Bookshelf 67% of reviewers reported a positive effect, while 13% reported a negative effect. https://naturalmedicines.therapeuticresearch.com. It works more slowly and lasts for about 12 hours, so you only need to take it once a day. Taking erectile dysfunction medications or drinking alcohol while taking isosorbide mononitrate (Monoket) can cause your blood pressure to get dangerously low, which can be life-threatening. Danshen can interact strongly with some heart medicines, such as: Evening primrose may raise your risk of bleeding if you also take a blood thinner, such as: Garlic may raise your risk of bleeding if you also take a blood thinner, such as: Ginkgo biloba may raise your risk of bleeding if you also take a blood thinner, such as: If you take ginseng with warfarin, it may lessen how well warfarin works. . To provide you with the most relevant and helpful information, and understand which This activity describes the indications, action, and contraindications for isosorbide as a valuable agent in treating angina pectoris due to coronary artery disease, heart failure with reduced . Conclusions: Does isosorbide mononitrate (Monoket) lower blood pressure? This medication belongs to a class of drugs known as nitrates. Be sure to follow your provider's instructions about when to take isosorbide mononitrate (Monoket). https://naturalmedicines.therapeuticresearch.com. Highly clinically significant. sharing sensitive information, make sure youre on a federal It is important for you to keep a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. Botanical medicine A modern perspective. This medicine is available only with your doctor's prescription. Can isosorbide mononitrate cause problems? As precautionary measure, breast-feeding should be discontinued during treatment with isosorbide mononitrate.
Isosorbide Manufacturing: An In-Depth Look at Production Costs and Any use of this site constitutes your agreement to the Terms and Conditions and Privacy Policy linked below. 2006 Apr;95(4):217-23. doi: 10.1007/s00392-006-0367-x. Liperoti R, et al. We study millions of patients and 5,000 more each day. Yet many herbal supplements may interact with heart disease medicines. Isosorbide tablets are also used with other medications to treat heart failure. To avoid this, if you are taking more than one dose a day, your doses may not be prescribed at equal intervals throughout the day. There are a number of medications that your doctor can prescribe in place of isosorbide mononitrate (Monoket). Be sure to mention any of the following: aspirin; beta blockers such as atenolol (Tenormin, Tenoretic), carteolol , labetalol (Trandate), metoprolol (Lopressor, Toprol-XL, in Dutoprol, in Lopressor HCT), nadolol (Corgard, in Corzide), propranolol (Hemangeol, Inderal, Innopran), sotalol (Betapace, Sorine, Sotylize), and timolol; calcium channel blockers such as amlodipine (Norvasc, in Amturnide, in Tekamlo), diltiazem (Cardizem, Cartia, Dilt-CD, others), felodipine (Plendil), isradipine, nifedipine (Adalat CC, Afeditab, Procardia), and verapamil (Calan, Covera, Verelan); ergot-type medications such as bromocriptine (Cycloset, Parlodel), cabergoline, dihydroergotamine (D.H.E. Please note that only the generic name of each medication is listed below. Headache is often a sign that this medication is working. We comply with the HONcode standard for trustworthy health information. Saper RB. Call your doctor if you have any unusual problems while you are taking this medication. Methods: Data were assessed for carryover and time effects. US residents can call their local poison control center at 1-800-222-1222. Before having surgery, tell your doctor or dentist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products). All rights reserved. Isosorbide mononitrate (Monoket) is available as a generic medication and may be significantly cheaper compared to the brand version. If you are a Mayo Clinic patient, this could This medication performs a vasodilatory function and is therefore used as a treatment for high blood pressure. 8600 Rockville Pike Imdur (isosorbide mononitrate) Extended Release and Isordil (isosorbide dinitrate) are vasodilators indicated for the prevention of angina pectoris due to coronary artery disease.. Side effects of Imdur and Isordil that are similar include headache and dizziness.. Side effects of Isordil that are different from Imdur include weakness and skin changes such as redness, tingling, or warmth. tell your doctor if you may be dehydrated, if you have recently had a heart attack, or if you have or have ever had heart failure, low blood pressure, or hypertrophic cardiomyopathy (thickening of the heart muscles). Mayo Clinic does not endorse companies or products. Talk to your doctor about the possible risks of using this medication for your condition. If you do not remember until your next dose is nearly due, then leave out the forgotten dose and take your next dose when it is due. Isosorbide mononitrate is also sometimes prescribed alongside other medicines for people with heart failure. Tell your doctor if this medication stops working well (for example, you have more frequent or worsening chest pain). Do not let anyone else take your medication. Duplication for commercial use must be authorized by ASHP. Only your doctor, nurse, or pharmacist can provide you with advice on what is safe and effective for you. Isosorbide mononitrate should not be used in patients with severe anaemia, severe hypotension, closed angle glaucoma or severe hypovolaemia.Isosorbide mononitrate may give rise to postural hypotension and syncope in some patients. This is so your doctor can check on your progress. This should pass after a few days. You may opt-out of email communications at any time by clicking on Do not try to change the times or the way that you take isosorbide in order to avoid headaches because then the medication may not work as well. Review/update the Take them to your local pharmacy which will dispose of them for you. For even more savings, use a GoodRx coupon and pay just a fraction of the retail price. McGraw Hill; 2022. https://accessmedicine.mhmedical.com/search. What is the difference between the immediate-release (IR) and extended-release (ER) versions of isosorbide mononitrate (Monoket)? eCollection 2021. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. It is best not to drink alcohol while you are on isosorbide mononitrate. Can cause dizziness, especially when you change positions, Interacts with erectile dysfunction medications. Continue to take isosorbide even if you feel well. Change positions slowly until your body is used to the medication. Isosorbide-5-mononitrate ISMN usually begins acting within 30 minutes and its effects last six to eight hours. Do not take a double dose to make up for a missed one. An official website of the United States government. Nitrates in the management of acute coronary syndrome. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. Does Alcohol Raise Your Blood Pressure? If tolerance is suspected during the use of transdermal patches they should be left off for 8-12 hours (usually overnight) in each 24 hours; in the case of modified-release tablets of isosorbide dinitrate (and . A total of 195 drugs are known to interact with isosorbide mononitrate: A total of 330 drugs are known to interact with aspirin: A total of 239 drugs are known to interact with nitroglycerin: No known alcohol/food interactions. Select a condition to view a list of medication options. Accessed Sept. 7, 2022. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API). Information is also available online at https://www.poisonhelp.org/help. Your doctor may tell you to take a pain reliever to treat your headaches. Dehydration in Buspar, how severe and when it was recovered? Do not store in the bathroom. you should know that isosorbide may cause dizziness, lightheadedness, and fainting when you get up too quickly from a lying position, or at any time, especially if you have been drinking alcoholic beverages. Take isosorbide exactly as directed. This information is aggregated and used to produce personalized reports that patients can reference.
Isosorbide mononitrate - Wikipedia Weight Loss for Health and Longevity, Science Reveals How Red Meat Harms the Heart, Flavored Vapes Still in Stores Despite Federal Ban, New COVID Antiviral Pills: What You Need to Know, Dr. Whyte's Book: Take Control of Your Cancer Risk, WebMD Loses Cherished Leader Kristy Hammam, Health News and Information, Delivered to Your Inbox, List Isosorbide Mononitrate side effects by likelihood and severity. daily and increasing to 40 mg three times daily as necessary, given at 8 AM, 1 PM, and 6 PM), isosorbide mononitrate (starting at 30 mg/day in the morning and increasing to 120 mg/day as necessary), or a transdermal. coma (loss of consciousness for a period of time). It took me a few weeks to adapt to it, but the effect on preventing chest pain was dramatic. Results: Let your provider know if they are excessive. Symptoms of overdose may include: slow heartbeat, vision changes, severe nausea/vomiting, sweating, cold/clammy skin, bluish fingers/toes/lips. The unwanted effects often improve as your body adjusts to the new medicine, but speak with your doctor or pharmacist if any of the following continue or become troublesome. What happens if I stop taking isosorbide mononitrate (Monoket)? Some products have ingredients that could worsen your heart failure. Isosorbide mononitrate vs. Amlodipine besylate, Isosorbide mononitrate vs. Bisoprolol fumarate, Isosorbide mononitrate vs. Diltiazem hydrochloride, Isosorbide mononitrate vs. Isosorbide dinitrate, Isosorbide mononitrate vs. Metoprolol succinate, Isosorbide mononitrate vs. Metoprolol tartrate, Isosorbide mononitrate vs. Nitrolingual pumpspray, Isosorbide mononitrate and Aspirin (7,880 reports), Isosorbide mononitrate and Furosemide (6,020 reports), Isosorbide mononitrate and Amlodipine (3,554 reports), Isosorbide mononitrate and Simvastatin (3,508 reports), Isosorbide mononitrate and Omeprazole (3,422 reports), Isosorbide mononitrate and Lisinopril (3,099 reports), Isosorbide mononitrate and Metformin (2,822 reports), Isosorbide mononitrate and Carvedilol (2,589 reports), Isosorbide mononitrate and Clopidogrel (2,524 reports), Isosorbide mononitrate and Acetylsalicylic acid (2,355 reports). (3) The overall number of headache attacks in the first period of active treatment was significantly higher than in the second period irrespective of the dosages given. While both isosorbide mononitrate (Monoket) and nitroglycerin (Nitrostat) are both nitrate vasodilators, they are not the same medication. The narrowing makes it more difficult for blood to flow to your heart muscle. Mayo Clinic. CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. Disclaimer. Do not drive, use machinery, or do anything that needs alertness until you can do it safely.
Nitrate-induced headache in patients with stable angina pectoris Browse Drugs and Medicines. The most common side-effect is headache. Selected from data included with permission and copyrighted by First Databank, Inc. There are 7 disease interactions with isosorbide mononitrate which include: Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. This site complies with the HONcode standard for trustworthy health information: verify here. You may report side effects to the FDA at 1-800-FDA-1088. Treatment and prognosis of heart failure with preserved ejection . 1998 Oct;61(10):577-83.
Isosorbide mononitrate (Monoket): Basics, Side Effects & Reviews - GoodRx WebMD does not provide medical advice, diagnosis or treatment. Saw palmetto might make your risk of bleeding higher if you also take a blood thinner, such as: It's not suggested to take St. John's wort if you take blood thinners. Background: Nitrates, although important for the management of angina pectoris, cause significant headache in many patients. The list below does not include all possible drug interactions with isosorbide mononitrate (Monoket). Isosorbide controls chest pain but does not cure coronary artery disease. Isosorbide-2,5-dinitrate and isosorbide-5-mononitrate, the low-potent organic nitrates, are directly metabolized in the endoplasmic reticulum of the vascular smooth muscle cells via cytochrome P450 enzymes, resulting in direct production of nitric oxide (Mnzel et al., 2005).In contrast, the highly potent organic nitrates such as glyceryl trinitrate (GTN) and pentaerythritile tetranitrate . AskMayoExpert.
Organic Nitrate - an overview | ScienceDirect Topics Isosorbide mononitrate tablets and capsules are not suitable to take to treat the pain of an angina attack.